Disputas - Master i kjemi Yngve Guttormsen

Avhandlingen er tilgjengelig her! / The doctoral thesis is available here!

Disputasen strømmes og et opptak vil være tilgjengelig i et døgn.
The defense will be streamed, and a recording of the disputation will be available for 24 hours.


Prøveforelesning over oppgitt emne starter kl. 10.15 / The trial lecture starts at 10.15
Tittel/Title: "Late-stage isotopic labelling of pharmaceuticals"
Prøveforelesningen strømmes her / The trial lecture will be streamed here.

Disputasen starter kl. 12.15 / The defense starts at 12.15
Disputasen strømmes her / The defense will be streamed here.


Populærvitenskapelig sammendrag av avhandlingen/ Summary of the thesis:

Cancer remains one of the leading causes of death, and better tools to detect and treat it are urgently needed.
In this project, I developed small molecules to stop cancer-related enzymes called kinases and others that carry radioactive labels to scan for brain tumors with high levels of kinases.
Here, I describe the design, synthesis, and radioactive labeling of molecules for diagnosis and treatment. The molecules were tested in different models, from single cancer-related proteins and cells to animal models with cancer.
This work may lead to improved cancer treatment and more accurate imaging – especially for aggressive brain tumors.


Veiledere/ Supervisors:
Hovedveileder/Main supervisor:
Professor Jørn H. Hansen, Institutt for kjemi, Fakultet for naturvitenskap og teknologi, UiT Norges arktiske universitet.
Biveileder/supervisor:
Førsteamanuensis Rune Sundset, Institutt for klinisk medisin, , Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.


Bedømmelseskomité/Defensecomitee:
Anna Kirjavainen, University of Turku – 1. opponent.
Marius Aursnes, NMBU – 2. opponent.
Marius Haugland-Grange, Institutt for kjemi, Fakultet for naturvitenskap og teknologi, UiT Norges arktiske universitet – leder av komité.


Disputasleder/ Leader of defense: 
Professor Maja-Lisa Løchen, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.