Tom Dønnem
Job description
Leder Translasjonell Kreftforskningsgruppe, IKM. Bistilling som overlege ved kreftavdelingen (UNN) og Enhet for Lindrende Behandling (UNN).
Dagny,
Thomas Karsten,
Mona Irene,
Egil Støre,
Ilona Halva,
Erna-Elise
et al.:
High density of TCF1+ stem-like tumor-infiltrating lymphocytes is associated with favorable disease-specific survival in NSCLC
Mehrdad,
Masoud,
Biagio,
Joao V,
Alessio,
Fabrizio
et al.:
Deep Learning Model for Predicting Immunotherapy Response in Advanced Non-Small Cell Lung Cancer
Per Niklas Benzler,
Hasse,
Henrik,
Markus Kreutzer,
Tom,
Johan Fredrik
et al.:
Algorithm for predicting valvular heart disease from heart sounds in an unselected cohort
Erna-Elise,
Sigve,
Mehrdad,
Mona Irene,
Ana Paola,
Mette
et al.:
Impact of microvessel patterns and immune status in NSCLC: a non-angiogenic vasculature is an independent negative prognostic factor in lung adenocarcinoma
Mehrdad,
Sigve,
K.,
Erna-Elise,
Thomas Karsten,
Lill-Tove Rasmussen
et al.:
Machine learning-based immune phenotypes correlate with STK11/KEAP1 co-mutations and prognosis in resectable NSCLC: a sub-study of the TNM-I trial
Bente,
Tom,
May Lill
:
Dying at “home” - a qualitative study of end-of-life care in rural Northern Norway from the perspective of health care professionals
Therese Haugdahl,
Anne Heidi,
Ilona Halva,
Robin,
Erna-Elise,
Tom
et al.:
Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer
Mehrdad,
Elio,
Biagio,
Lynette M. Sholl,
Weiwei,
Joao V.
et al.:
Association of machine learning-based assessment of tumor-infiltrating lymphocytes on standard histologic images with outcomes of immunotherapy in patients with NSCLC
JAMA Oncology 17. November 2022 DOI
Therese H.,
Marit,
Tom,
Hege,
Charlotta,
Eiliv
et al.:
Transcriptomic signals in blood prior to lung cancer focusing on time to diagnosis and metastasis
Sissel Gyrid Freim,
Yan Dai,
Elisabeth Fritzke,
Thomas,
Tarje Onsøien,
Anine Larsen
et al.:
The prognostic effect of KRAS mutations in non-small cell lung carcinoma revisited: A norwegian multicentre study
Maria Jenvin,
Sigve,
Mehrdad,
Mona I.,
Lise Martine,
Tom
et al.:
Overexpression of mir-20a-5p in tumor epithelium is an independent negative prognostic indicator in prostate cancer—a multi-institutional study
Maria Jenvin,
Sigve,
Mehrdad,
Mona Irene,
Lise Martine,
Roy M.
et al.:
High expression of miR-17-5p in tumor epithelium is a predictor for poor prognosis for prostate cancer patients
Mehrdad,
Thomas Karsten,
Simin,
Thomas,
Erna-Elise,
Marte
et al.:
Tertiary lymphoid structure score: a promising approach to refine the TNM staging in resected non-small cell lung cancer
British Journal of Cancer 2021 DOI
Thomas Karsten,
Erna-Elise,
Sigve,
Mehrdad,
Roy M.,
Lill-Tove Rasmussen
et al.:
Digitally quantified CD8+ cells: the best candidate marker for an immune cell score in non-small cell lung cancer?
Bente,
Sigve,
Helge,
Tom
:
Evaluating a centralised cancer support centre in the remote region of Northern Norway
Elin,
Sigve,
Christian,
Mehrdad,
Nora,
Samer
et al.:
MicroRNA 141 is associated to outcome and aggressive tumor characteristics in prostate cancer
Mehrdad,
Lill-Tove,
Simin,
Erna-Elise,
Elin,
Sigve
et al.:
Prognostic Value of Macrophage Phenotypes in Resectable Non–Small Cell Lung Cancer Assessed by Multiplex Immunohistochemistry
Thomas Karsten,
Mehrdad,
Turid,
Jørg,
Luigi de,
Tom
et al.:
Differential prognostic impact of platelet-derived growth factor receptor Expression in NSCLC
Elin,
Sigve,
Samer,
Mehrdad,
Yngve,
Mona Irene
et al.:
Low expression of miR-424-3p is highly correlated with clinical failure in prostate cancer
Tom,
Andrew,
Elizabeth A.,
Kevin C.,
Peter B.,
Robert S.
et al.:
Non-angiogenic tumours and their influence on cancer biology
Nature Reviews Cancer 2018 DOI
Kaja Konstanse,
Charles,
Thea K.W.,
Thomas Karsten,
Erna Elise,
Mona Irene
et al.:
A gender specific improved survival related to stromal miR-143 and miR-145 expression in non-small cell lung cancer
Thea K.W.,
Elin,
Sigve,
Kaja Konstanse,
Mehrdad,
Tom
et al.:
Progesterone receptors in prostate cancer: Progesterone receptor B is the isoform associated with disease progression
Yury,
Sigve,
Charles,
Bjørn,
Karina Standahl,
Helge
et al.:
Transcription factor PAX6 as a novel prognostic factor and putative tumour suppressor in non-small cell lung cancer
Mehrdad,
Thomas Karsten,
Stig Manfred,
Elin,
Erna Elise,
Sigurd
et al.:
Evaluation of tumor-infiltrating lymphocytes using routine H&E slides predicts patient survival in resected non-small cell lung cancer
Human Pathology 2018 DOI
Sigurd,
Mehrdad,
Inigo Zubiavrre,
Elin,
Samer,
Erna Elise
et al.:
LAG-3 in Non-Small-cell Lung Cancer: Expression in Primary Tumors and Metastatic Lymph Nodes Is Associated With Improved Survival
Clinical Lung Cancer 2018 DOI
Thomas Karsten,
Mehrdad,
Turid,
Arne,
Carina,
Roy M.
et al.:
Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer
Tom,
Micklem,
Pezzella
:
Evolution and cancer (Chapter 3), Oxford Textbook of Cancer Biology
Oxford University Press 2019
Elio,
falah,
Masoud,
Amin,
Lill-Tove Rasmussen,
Tom
et al.:
Artificial Intelligence-powered analysis of the tumor immune microenvironment in primary and metastatic colorectal cancer
2024
falah,
Sigve,
Erna-Elise,
Masoud,
Elin Helmine,
Sissel Gyrid Freim
et al.:
Integrating Artificial intelligence (AI)-based lymphocytic infiltration assessment in early-stage NSCLC: A sub-study of the TNM-I trial
2024
Bente,
Tom,
May Lill
:
Home-death in Rural North Norway - Health Care Professionals Perspectives
2023
Mehrdad,
Masoud,
Elio,
Biagio,
Joao,
Alessio
et al.:
Artificial intelligence algorithm developed to predict immune checkpoint inhibitors efficacy in non–small-cell lung cancer
2023
Kjetil,
Hege Elisabeth Giercksky,
Eline,
Line,
Egil Støre,
Terje C.
et al.:
A national precision cancer medicine implementation initiative for Norway
Mehrdad,
Elio,
Biagio,
Lynette M.,
Weiwei,
Joao V
et al.:
Computational pathology by Artificial Intelligence (AI) on quantifying the lymphocytic infiltration predicts the immunotherapy response in NSCLC
2022
Åslaug,
Hege Elisabeth Giercksky,
Gro Live,
Khalid Ibrahim,
Yvonne,
Thomas
et al.:
Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway (Journal of Translational Medicine, (2022), 20, 1, (225), 10.1186/s12967-022-03432-5)
Journal of Translational Medicine 2022 DOI
Mehrdad,
Elio,
Biagio,
Lynette M.,
Joao,
Alessio
et al.:
Digital quantification of lymphocytic infiltration on routine H&E images and immunotherapy response in non-small cell lung cancer
2022
Mehrdad,
Elio,
Biagio,
Lynette M.,
Weiwei,
Joao
et al.:
Artificial intelligence in digital pathology approach identifies the predictive impact of tertiary lymphoid structures with immune-checkpoints therapy in NSCLC
2022
Ilona H.,
Therese Haugdahl,
Anne Heidi,
Robin,
Erna-Elise,
Tom
et al.:
Increased Levels of mRNAs and miRNAs Associated with Imminent and Advanced Lung Cancer
Journal of Thoracic Oncology 2022 DOI
Åslaug,
Hege Elisabeth Giercksky,
Gro Live,
Khalid Ibrahim,
Yvonne,
Thomas
et al.:
Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
Therese Haugdahl,
Ilona Halva,
Anne Heidi,
Robin,
Erna Elise,
Tom
et al.:
Increased levels of mRNAs and miRNAs associated with imminent and advanced lung cancer
2022
Sigve,
Tom
:
Krafttak mot kreft
14. März 2019
Tom,
Sigve
:
Jakter på kroppens krigerceller
18. September 2019
Tom
:
Lungekreftforskning i et samfunnspersepktiv
2019
Tom
:
Er angiogenese en "hallmark of cancer"? - paradigmeskifte og betydning for behandling
BestPractice nordic 2019
Tom,
Sigve
:
Jakter på kroppens krigerceller
05. September 2019
Kaja Konstanse,
Thea K.W.,
Mehrdad,
Elin,
Tom,
Thomas Karsten
et al.:
Corrigendum to "Prognostic relevance of estrogen receptor α, β and aromatase expression in non-small cell lung cancer" [Steroids 113 (2016) 5-13]
Steroids 2018 DOI
Tom
:
Kreftsvulsten er mer komplisert enn forskerer tidligere har trodd
25. Juni 2018
Tom
:
Kræftsvulster er mere komplicerede, end forskerne tidligere antaget
19. Juli 2018
Tom
:
Knuser sentral sannhet innen kreftforskning
16. Mai 2018
Tom
:
Tumours are more complicated than previously believed
04. Juli 2018
Sigve,
Tom,
Bodil,
Kari Margrethe,
Tone,
Bente
:
Palliative indicators in a university hospital - a cross-sectional prevalence study combined with ESAS-r symptom assesment and follow up of death
2017
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Research interests
Hovedfokus på translasjonell kreftforskning relatert til tumor immunologi og angiogense ved lungekreft. I tillegg forskning relatert persontilpasset medisin på tvers av flere krefttyper samt forskning knyttet til palliativ kreftbehandling.
Teaching
Fagenhetsleder kreft. Medlem av nasjonal eksamenskomite 6. års medisinstudenter.